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NPRL2 Antibody

CAT: 0223-58-740Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-740Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs.
NCBI Gene ID
10641
Swiss Prot
Q8WTW4
Accession Number
Q8WTW4
Host
Rabbit
Reactivity
Human
Immunogen
This NPRL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-373 amino acids from the C-terminal region of human NPRL2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
44 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NPRL2
NCBI Official Name
Nitrogen permease regulator 2-like protein
NCBI Organism
Homo sapiens
Background Reference 01
Spielewoy, N., et al. Eukaryotic Cell 9 (4) :592-601 (2010)
Background Reference 02
Otani, S., et al.Surg Oncol 100 (5) :358-363 (2009)
Background Reference 03
Neklesa, T.K., et al. PLoS Genet. (6), E1000515 (2009) :
Background Reference 04
Anedchenko, E.A., et al. Mol. Biol. (Mosk.) 42 (6) :965-976 (2008)
Other Product Names
Nitrogen permease regulator 2-like protein, NPR2-like protein, Gene 21 protein, G21 protein, Tumor suppressor candidate 4, NPRL2, TUSC4
Tested Applications
WB
Protein ID
47117604
Physical Properties
Liquid

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