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OBFC1 Antibody

CAT: 0223-58-735Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-735Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
OBFC1 and C17ORF68 (MIM 613129) are subunits of an alpha accessory factor (AAF) that stimulates the activity of DNA polymerase-alpha-primase (see MIM 176636), the enzyme that initiates DNA replication (Casteel et al., 2009 [PubMed 19119139]) . OBFC1 also appears to function in a telomere-associated complex with C17ORF68 and TEN1 (C17ORF106; MIM 613130) (Miyake et al., 2009 [PubMed 19854130]) .
NCBI Gene ID
79991
Swiss Prot
Q9H668
Accession Number
Q9H668
Host
Rabbit
Reactivity
Human
Immunogen
This OBFC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 amino acids from the C-terminal region of human OBFC1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
42 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
OBFC1
NCBI Official Name
CST complex subunit STN1
NCBI Organism
Homo sapiens
Background Reference 01
Levy, D., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (20) :9293-9298 (2010)
Background Reference 02
Miyake, Y., et al. Mol. Cell 36 (2) :193-206 (2009)
Background Reference 03
Wan, M., et al. J. Biol. Chem. 284 (39) :26725-26731 (2009)
Background Reference 04
Casteel, D.E., et al. J. Biol. Chem. 284 (9) :5807-5818 (2009)
Other Product Names
CST complex subunit STN1, Oligonucleotide/oligosaccharide-binding fold-containing protein 1, Suppressor of cdc thirteen homolog, OBFC1, STN1
Tested Applications
WB
Protein ID
62900737
Physical Properties
Liquid

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