OBFC1 Antibody

• Background:

  OBFC1 and C17ORF68 (MIM 613129) are subunits of an alpha accessory factor (AAF) that stimulates the activity of DNA polymerase-alpha-primase (see MIM 176636), the enzyme that initiates DNA replication (Casteel et al., 2009 [PubMed 19119139]) . OBFC1 also appears to function in a telomere-associated complex with C17ORF68 and TEN1 (C17ORF106; MIM 613130) (Miyake et al., 2009 [PubMed 19854130]) .

• NCBI Gene ID:

  79991

• Swiss Prot:

  Q9H668

• Accession Number:

  Q9H668

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This OBFC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 amino acids from the C-terminal region of human OBFC1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  42 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  OBFC1

• NCBI Official Name:

  CST complex subunit STN1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Levy, D., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (20) :9293-9298 (2010)

• Background Reference 02:

  Miyake, Y., et al. Mol. Cell 36 (2) :193-206 (2009)

• Background Reference 03:

  Wan, M., et al. J. Biol. Chem. 284 (39) :26725-26731 (2009)

• Background Reference 04:

  Casteel, D.E., et al. J. Biol. Chem. 284 (9) :5807-5818 (2009)

• Other Product Names:

  CST complex subunit STN1, Oligonucleotide/oligosaccharide-binding fold-containing protein 1, Suppressor of cdc thirteen homolog, OBFC1, STN1

• Tested Applications:

  WB

• Protein ID:

  62900737

• Physical Properties:

  Liquid