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ZNRF1 Antibody

CAT: 0223-58-699Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-699Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
In a study identifying genes in rat that are upregulated in response to nerve damage, a gene which is highly expressed in ganglia and in the central nervous system was found. The protein encoded by the rat gene contains both a zinc finger and a RING finger motif and is localized in the endosome/lysosome compartment, indicating that it may be involved in ubiquitin-mediated protein modification. The protein encoded by this human gene is highly similar in sequence to that encoded by the rat gene. [provided by RefSeq].
NCBI Gene ID
84937
Swiss Prot
Q8ND25
Accession Number
Q8ND25
Host
Rabbit
Reactivity
Human
Immunogen
This ZNRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-86 amino acids from the Central region of human ZNRF1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
24 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ZNRF1
NCBI Official Name
E3 ubiquitin-protein ligase ZNRF1
NCBI Organism
Homo sapiens
Background Reference 01
Dastani, Z., et al. Eur. J. Hum. Genet. 18 (3) :342-347 (2010)
Background Reference 02
Yoshida, K., et al. Biochem. Biophys. Res. Commun. 389 (3) :506-511 (2009)
Background Reference 03
Markson, G., et al. Genome Res. 19 (10) :1905-1911 (2009)
Background Reference 04
Van Wijk, S.J., et al. Mol. Syst. Biol. 5, 295 (2009) :
Other Product Names
E3 ubiquitin-protein ligase ZNRF1, 632-, Nerve injury-induced gene 283 protein, Zinc/RING finger protein 1, ZNRF1, NIN283
Tested Applications
WB
Protein ID
126253846
Physical Properties
Liquid

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