ASB3 Antibody

• Background:

  The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but some of the full length sequences are not known.

• NCBI Gene ID:

  10030265251130

• Swiss Prot:

  Q9Y575

• Accession Number:

  Q9Y575

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This ASB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-42 amino acids from the N-terminal region of human ASB3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  58 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  ASB3

• NCBI Official Name:

  Ankyrin repeat and SOCS box protein 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Yang, Q., et al. BMC Med. Genet.SUPPL 1, S12 (2007) Chung, A.S., et al. Mol. Cell. Biol. 25 (11) :4716-4726 (2005) Kile, B.T., et al. Trends Biochem. Sci. 27 (5) :235-241 (2002) Kile, B.T., et al. Mol. Cell. Biol. 21 (18) :6189-6197 (2001) Kile, B.T., et al. Gene 258 (1-2), 31-41 (2000) :

• Other Product Names:

  Ankyrin repeat and SOCS box protein 3, ASB-3, ASB3

• Tested Applications:

  WB

• Protein ID:

  20532004

• Physical Properties:

  Liquid