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KCNC1 Antibody

CAT: 0223-57-805Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-805Size:400 µL
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Background
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Multiple transcript variants encoding different isoforms have been inferred for this gene based on orthologous loci.
NCBI Gene ID
3746
Swiss Prot
P48547
Accession Number
P48547
Host
Rabbit
Reactivity
Human
Immunogen
This KCNC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 479-508 amino acids from the C-terminal region of human KCNC1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
58 kDa
Fragment
Rabbit Ig
Symbol
KCNC1
NCBI Official Name
Potassium voltage-gated channel subfamily C member 1
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Background Reference 03
Wang, Z., et al. J. Gen. Physiol. 133 (4) :361-374 (2009)
Background Reference 04
Gutman, G.A., et al. Pharmacol. Rev. 57 (4) :473-508 (2005)
Other Product Names
Potassium voltage-gated channel subfamily C member 1, NGK2, Voltage-gated potassium channel subunit Kv31, Voltage-gated potassium channel subunit Kv4, KCNC1
Tested Applications
WB, IHC-P
Protein ID
1352085
Physical Properties
Liquid

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