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CDCA4 Antibody

CAT: 0223-58-624Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-624Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulaton of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for this gene. Two pseudogenes have also been identified on chromosome 1.
NCBI Gene ID
55038
Swiss Prot
Q9BXL8
Accession Number
Q9BXL8
Host
Rabbit
Reactivity
Human
Immunogen
This CDCA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-190 amino acids from the C-terminal region of human CDCA4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
26 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CDCA4
NCBI Official Name
Cell division cycle-associated protein 4
NCBI Organism
Homo sapiens
Background Reference 01
Tategu, M., et al. Biochimie 90 (10) :1515-1522 (2008)
Background Reference 02
Wang, L., et al. Cell Motil. Cytoskeleton 65 (7) :581-593 (2008)
Background Reference 03
Hayashi, R., et al. J. Biol. Chem. 281 (47) :35633-35648 (2006)
Background Reference 04
Walker, M.G. Curr Cancer Drug Targets 1 (1) :73-83 (2001)
Other Product Names
Cell division cycle-associated protein 4, Hematopoietic progenitor protein, CDCA4, HEPP
Tested Applications
WB
Protein ID
32699606
Physical Properties
Liquid

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