CNTROB Antibody

• Background :

  CNTROB is a centrosomal protein that interacts with BRCA2 (MIM 600185) and is required for centriole duplication and cytokinesis (Zou et al., 2005 [PubMed 16275750]) .[supplied by OMIM].

• NCBI Gene ID :

  116840

• Swiss Prot :

  Q8N137

• Accession Number :

  Q8N137

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This CNTROB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-430 amino acids from the Central region of human CNTROB.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Cell Cycle

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  101 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  CNTROB

• NCBI Official Name :

  Centrobin

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Lee, J., et al. J. Biol. Chem. 285 (33) :25476-25484 (2010)

• Background Reference 02 :

  Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :

• Background Reference 03 :

  Jeffery, J.M., et al. Oncogene 29 (18) :2649-2658 (2010)

• Background Reference 04 :

  Song, L., et al. Cell. Signal. 22 (5) :857-864 (2010)

• Other Product Names :

  Centrobin, Centrosomal BRCA2-interacting protein, LYST-interacting protein 8, CNTROB, LIP8

• Tested Applications :

  WB

• Protein ID :

  74728485

• Physical Properties :

  Liquid