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HOXD4 Antibody

CAT: 0223-58-503Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-503Size:400 µL
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Background
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined.
NCBI Gene ID
3233
Swiss Prot
P09016
Accession Number
P09016
Host
Rabbit
Reactivity
Human
Immunogen
This HOXD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the C-terminal region of human HOXD4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Chicken, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
28 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
HOXD4
NCBI Official Name
Homeobox protein Hox-D4
NCBI Organism
Homo sapiens
Background Reference 01
Zhang, H., et al. Acta Pharmacol. Sin. 31 (8) :977-983 (2010)
Background Reference 02
Ester, A.R., et al. Am. J. Med. Genet.149A (12), 2745-2752 (2009) :
Background Reference 03
Yerges, L.M., et al. J. Bone Miner. Res. 24 (12) :2039-2049 (2009)
Background Reference 04
Tan, Y., et al. BMC Mol. Biol. 10, 12 (2009) :
Other Product Names
Homeobox protein Hox-D4, Homeobox protein HHOC13, Homeobox protein Hox-4B, Homeobox protein Hox-51, HOXD4, HOX4B
Tested Applications
WB
Protein ID
20141491
Physical Properties
Liquid