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HOXD8 Antibody

CAT: 0223-60-085Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-085Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function.
NCBI Gene ID
3234
Swiss Prot
P13378
Accession Number
P13378
Host
Rabbit
Reactivity
Human
Immunogen
This HOXD8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-270 amino acids from the C-terminal region of human HOXD8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
32 kDa
Fragment
Rabbit Ig
Symbol
HOXD8
NCBI Official Name
Homeobox protein Hox-D8
NCBI Organism
Homo sapiens
Background Reference 01
Ester, A.R., et al. Am. J. Med. Genet.149A (12), 2745-2752 (2009) :
Background Reference 02
Yerges, L.M., et al. J. Bone Miner. Res. 24 (12) :2039-2049 (2009)
Background Reference 03
Harada, K., et al. J. Cell. Sci. 122 (PT 21), 3923-3930 (2009) :
Background Reference 04
Goodman, F.R. Am. J. Med. Genet. 112 (3) :256-265 (2002)
Other Product Names
Homeobox protein Hox-D8, Homeobox protein Hox-4E, Homeobox protein Hox-54, HOXD8, HOX4E
Tested Applications
WB, IF
Protein ID
13124737
Physical Properties
Liquid

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