HOXD3 Antibody

• Background:

  HOXD3 (homeobox D3) belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that remove the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. HOXD3 may play a role in the regulation of cell adhesion processes.

• NCBI Gene ID:

  3232

• Swiss Prot:

  P31249

• Accession Number:

  NP_008829

• Host:

  Rabbit

• Reactivity:

  Human, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HOXD3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HOXD3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  46 kDa

• Applications Notes:

  HOXD3 antibody can be used for detection of HOXD3 by ELISA at 1:62500. HOXD3 antibody can be used for detection of HOXD3 by western blot at 1.0-2.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  HOXD3

• NCBI Official Name:

  Homeobox D3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Boudreau, N.J., et al., (2004) J.Biol.Chem.279 (6), 4862-4868.

• Other Product Names:

  HOXD3, HOX4, HOX1D, HOX4A, Hox-4.1

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  19923391

• Physical Properties:

  Liquid