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HOXC4 Antibody

CAT: 0223-57-681Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-681Size:400 µL
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Background
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC4, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants that encode the same protein have been described for HOXC4. Transcript variant one includes the shared exon, and transcript variant two includes only gene-specific exons.
NCBI Gene ID
3221
Swiss Prot
P09017
Accession Number
P09017
Host
Rabbit
Reactivity
Human
Immunogen
This HOXC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-225 amino acids from the C-terminal region of human HOXC4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
30 kDa
Fragment
Rabbit Ig
Symbol
HOXC4
NCBI Official Name
Homeobox protein Hox-C4
NCBI Organism
Homo sapiens
Background Reference 01
Park, S.R., et al. Nat. Immunol. 10 (5) :540-550 (2009)
Background Reference 02
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Background Reference 03
Wissmuller, S., et al. Nucleic Acids Res. 34 (6) :1735-1744 (2006)
Background Reference 04
Gong, L.G., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 22 (5) :497-501 (2005)
Other Product Names
Homeobox protein Hox-C4, Homeobox protein CP19, Homeobox protein Hox-3E, HOXC4, HOX3E
Tested Applications
WB, IHC-P
Protein ID
281185468
Physical Properties
Liquid

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