PRPS2 Antibody

• Background:

  PRPS2 is a phosphoribosyl pyrophosphate synthetase that plays a central role in the synthesis of purines and pyrimidines. The encoded protein catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate. Alternate splicing results in multiple transcript variants.

• NCBI Gene ID:

  5634

• Swiss Prot:

  P11908

• Accession Number:

  P11908

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PRPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-106 amino acids from the Central region of human PRPS2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Y, Bovine, Monkey, Mouse, Rat, Xenopus

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  35 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PRPS2

• NCBI Official Name:

  Ribose-phosphate pyrophosphokinase 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Mannava, S., et al. Cell Cycle 7 (15) :2392-2400 (2008)

• Background Reference 02:

  Tatibana, M., et al. Adv. Enzyme Regul. 35, 229-249 (1995) :

• Background Reference 03:

  Dawson, S.J., et al. J. Infect. 24 (3) :317-320 (1992)

• Background Reference 04:

  Ishizuka, T., et al. Biochim. Biophys. Acta 1130 (2) :139-148 (1992)

• Other Product Names:

  Ribose-phosphate pyrophosphokinase 2, PPRibP, Phosphoribosyl pyrophosphate synthase II, PRS-II, PRPS2

• Tested Applications:

  WB

• Protein ID:

  125583

• Physical Properties:

  Liquid