CD226 Antibody

• Background:

  CD226 is a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. [provided by RefSeq].

• NCBI Gene ID:

  10666

• Swiss Prot:

  Q15762

• Accession Number:

  Q15762

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CD226 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-335 amino acids from the C-terminal region of human CD226.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  39 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CD226

• NCBI Official Name:

  CD226 antigen

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lofgren, S.E., et al. Arthritis Rheum. 62 (11) :3404-3414 (2010)

• Background Reference 02:

  Carlsten, M., et al. Leukemia 24 (9) :1607-1616 (2010)

• Background Reference 03:

  Plant, D., et al. Ann. Rheum. Dis. 69 (8) :1548-1553 (2010)

• Background Reference 04:

  Alcina, A., et al. Genes Immun. 11 (5) :439-445 (2010)

• Other Product Names:

  CD226 antigen, DNAX accessory molecule 1, DNAM-1, CD226, CD226, DNAM1

• Tested Applications:

  WB

• Protein ID:

  317373338

• Physical Properties:

  Liquid