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HTR7 Antibody

CAT: 0223-58-454Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-454Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends.
NCBI Gene ID
3363
Swiss Prot
P34969
Accession Number
P34969
Host
Rabbit
Reactivity
Human
Immunogen
This HTR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 405-433 amino acids from the C-terminal region of human HTR7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
54 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
HTR7
NCBI Official Name
5-hydroxytryptamine receptor 7
NCBI Organism
Homo sapiens
Background Reference 01
Ruano, G., et al. Pharmacogenomics 11 (7) :959-971 (2010)
Background Reference 02
Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Background Reference 03
Corominas, R., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (1), 177-184 (2010) :
Background Reference 04
Wei, Z., et al. Prog. Neuropsychopharmacol. Biol. Psychiatry 33 (3) :547-551 (2009)
Other Product Names
5-hydroxytryptamine receptor 7, 5-HT-7, 5-HT7, 5-HT-X, Serotonin receptor 7, HTR7
Tested Applications
WB
Protein ID
8488960
Physical Properties
Liquid

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