TMOD1 Antibody

• Background:

  TMOD1 is a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin filaments and thereby influencing the structure of the erythrocyte membrane skeleton. Multiple transcript variants encoding the same protein have been found for this gene.

• NCBI Gene ID:

  7111

• Swiss Prot:

  P28289

• Accession Number:

  P28289

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This TMOD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-198 amino acids from the Central region of human TMOD1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  41 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  TMOD1

• NCBI Official Name:

  Tropomodulin-1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

• Background Reference 02:

  Kong, K.Y., et al. J. Biol. Chem. 281 (14) :9589-9599 (2006)

• Background Reference 03:

  Vera, C., et al. Arch. Biochem. Biophys. 444 (2) :130-138 (2005)

• Background Reference 04:

  Pawlak, G., et al. Int. J. Cancer 110 (3) :368-373 (2004)

• Other Product Names:

  Tropomodulin-1, Erythrocyte tropomodulin, E-Tmod, TMOD1, D9S57E, TMOD

• Tested Applications:

  WB

• Protein ID:

  135922

• Physical Properties:

  Liquid