TMOD3 Antibody

• Background:

  TMOD3 belongs to the tropomodulin family. It blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. This gene is a necessary element in receptor tyrosine kinase pathways, possibly as a tyrosine phosphorylation target. It is involved in regulation of RAF in the MAPK pathway and may also play a role in a MAPK-independent pathway.

• NCBI Gene ID:

  29766

• Swiss Prot:

  Q9NYL9

• Accession Number:

  NP_055362

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TMOD3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TMOD3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  39 kDa

• Applications Notes:

  TMOD3 antibody can be used for detection of TMOD3 by ELISA at 1:62500. TMOD3 antibody can be used for detection of TMOD3 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  TMOD3

• NCBI Official Name:

  Tropomodulin 3 (ubiquitous)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Weber, K.L., J. Cell. Sci. 120 (PT 20), 3625-3632 (2007) .

• Other Product Names:

  TMOD3, UTMOD

• Tested Applications:

  ELISA, WB

• Protein ID:

  7657649

• Physical Properties:

  Liquid