NCOA4 Antibody

• Background:

  This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma.

• NCBI Gene ID:

  8031

• Swiss Prot:

  Q13772

• Accession Number:

  Q13772

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This NCOA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 496-524 amino acids from the C-terminal region of human NCOA4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  70 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  NCOA4

• NCBI Official Name:

  Nuclear receptor coactivator 4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Sadow, P.M., et al. Endocr. Pathol. 21 (2) :73-79 (2010)

• Background Reference 02:

  Landa, I., et al. PLoS Genet. (9), E1000637 (2009) :

• Background Reference 03:

  Richardson, D.S., et al. Cancer Res. 69 (11) :4861-4869 (2009)

• Background Reference 04:

  Peng, Y., et al. Am. J. Pathol. 172 (1) :225-235 (2008)

• Other Product Names:

  Nuclear receptor coactivator 4, NCoA-4, Androgen receptor coactivator 70 kDa protein, 70 kDa AR-activator, 70 kDa androgen receptor coactivator, Androgen receptor-associated protein of 70 kDa, Ret-activating protein ELE1, NCOA4, ARA70, ELE1, RFG

• Tested Applications:

  WB

• Protein ID:

  8928226

• Physical Properties:

  Liquid