Products for Research Use Only
RegisterLogin

NCOA4 (IN) Antibody

CAT: 0223-9663-01Size: 0.02 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-9663-01Size:0.02 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
NCOA4 Antibody: Study showed that NCOA4-mediated ferritin complex degradation supplies iron to mitochondria. Loss of COPZ1 induces NCOA4 mediated autophagy and ferroptosis in glioblastoma cell lines. NCOA4-mediated ferritinophagy promoted inflammatory responses in periodontitis. Low expression of ferritinophagy-related NCOA4 gene in relation to unfavorable outcome and defective immune cells infiltration in clear cell renal carcinoma.
NCBI Gene ID
8031
Swiss Prot
Q13772
Accession Number
Q13772
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
9663
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
NCOA4 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1202 – Daudi Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: monkey (100%), gorilla (100%), dog (100%), horse (100%)
Buffer
NCOA4 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
NCOA4 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Applications Notes
WB: 0.5-1 μ g/mL; IHC: 1 μ g/mL; IF: 20 μ g/mL. Antibody validated: Western Blot in human, mouse and rat samples; Immunofluorescence in human samples and Immunohistochemistry in human, mouse and rat samples. All other applications and species not yet tested.
Isoform
Human NCOA4 has 4 isoforms, including isoform alpha (614aa, 69.7kD), isoform beta (287aa, 32.6kD), isoform 3 (630aa, 71.4kD) and isoform 4 (650aa, 73.6kD) . Mouse NCOA4 has at least one isoform (625aa, 70.4kD) . Rat NCOA4 has one isoform (622aa, 70.3kD) . 9663 can detect NCOA4 in human, mouse and rat.
Symbol
NCOA4
Positive Control 2
Cat. No. 1402 – Mouse Lung Lysate
NCBI Official Name
Nuclear receptor coactivator 4
NCBI Organism
Homo sapiens
Background Reference 01
Fujimaki et al. Mol Cell Biol. 2019; 39 (14) : e00010-19
Background Reference 02
Zhang et al. Oncogene. 2021; 40 (8) : 1425-1439
Background Reference 03
Guo et al. J Periodontal Res. 2021; 56 (3) : 523-534
Background Reference 04
Mou et al. BMC Cancer. 2021; 21 (1) :18
Other Product Names
NCOA4 Antibody: Nuclear receptor coactivator 4, NCoA-4, Androgen receptor coactivator 70 kDa protein, 70 kDa AR-activator, 70 kDa androgen receptor coactivator, Androgen receptor-associated protein of 70 kDa, Ret-activating protein ELE1, ARA70, ELE1, RFG
Tested Applications
ELISA, IHC, WB, IF
Protein ID
8928226
Physical Properties
Liquid

Related Products

CatalogName
19-801NCOA4 Antibody
58-335NCOA4 Antibody
9663PNCOA4 (IN) Peptide
63-996NCOA7 Antibody
19-075NCOA5 Antibody
25-071NCOA3 Antibody
13-552NCOA2 Antibody, KO Validated
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody

Alternative Products

CatalogName
GWB-MM593HNcoa4 Antibody

Popular Products