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HOXB8 Antibody

CAT: 0223-58-305Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-305Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.
NCBI Gene ID
3218
Swiss Prot
P17481
Accession Number
P17481
Host
Rabbit
Reactivity
Human
Immunogen
This HOXB8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-243 amino acids from the C-terminal region of human HOXB8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
28 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
HOXB8
NCBI Official Name
Homeobox protein Hox-B8
NCBI Organism
Homo sapiens
Background Reference 01
Kosaki, K., et al. Teratology 65 (2) :50-62 (2002)
Background Reference 02
Greer, J.M., et al. Neuron 33 (1) :23-34 (2002)
Background Reference 03
Knoepfler, P.S., et al. Oncogene 20 (39) :5440-5448 (2001)
Background Reference 04
Fujino, T., et al. Exp. Hematol. 29 (7) :856-863 (2001)
Other Product Names
Homeobox protein Hox-B8, Homeobox protein Hox-24, Homeobox protein Hox-2D, HOXB8, HOX2D
Tested Applications
WB
Protein ID
20141506
Physical Properties
Liquid

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