HOXB6 Antibody

• Background:

  This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer.

• NCBI Gene ID:

  3216

• Swiss Prot:

  P17509

• Accession Number:

  P17509

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This HOXB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-155 amino acids from the Central region of human HOXB6.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  25 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  HOXB6

• NCBI Official Name:

  Homeobox protein Hox-B6

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ferrai, C., et al. Mol. Biol. Cell 20 (15) :3543-3551 (2009)

• Background Reference 02:

  Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)

• Background Reference 03:

  Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

• Background Reference 04:

  Chen, T., et al. Eur. J. Hum. Genet. 15 (1) :23-28 (2007)

• Other Product Names:

  Homeobox protein Hox-B6, Homeobox protein Hox-22, Homeobox protein Hox-2B, Homeobox protein Hu-2, HOXB6, HOX2B

• Tested Applications:

  WB, IHC-P

• Protein ID:

  116242515

• Physical Properties:

  Liquid