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HOXB6 Antibody

CAT: 0223-56-006Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-006Size:400 µL
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Background
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer.
NCBI Gene ID
3216
Swiss Prot
P17509
Accession Number
P17509
Host
Rabbit
Reactivity
Mouse
Immunogen
This HOXB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-155 amino acids from the Central region of human HOXB6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
25 kDa
Fragment
Rabbit Ig
Symbol
HOXB6
NCBI Official Name
Homeobox protein Hox-B6
NCBI Organism
Homo sapiens
Background Reference 01
Ferrai, C., et al. Mol. Biol. Cell 20 (15) :3543-3551 (2009)
Background Reference 02
Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)
Background Reference 03
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Background Reference 04
Chen, T., et al. Eur. J. Hum. Genet. 15 (1) :23-28 (2007)
Other Product Names
Homeobox protein Hox-B6, Homeobox protein Hox-22, Homeobox protein Hox-2B, Homeobox protein Hu-2, HOXB6, HOX2B
Tested Applications
WB, IHC-P
Protein ID
116242515
Physical Properties
Liquid

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