LTB4R2 Antibody

• Background:

  Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.

• NCBI Gene ID:

  56413

• Swiss Prot:

  Q9NPC1

• Accession Number:

  Q9NPC1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This LTB4R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 333-361 amino acids from the C-terminal region of human LTB4R2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Obesity, Growth Factors

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  42 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  LTB4R2

• NCBI Official Name:

  Leukotriene B4 receptor 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kim, G.Y., et al. J. Immunol. 184 (7) :3946-3954 (2010)

• Background Reference 02:

  Ryu, H.C., et al. J. Invest. Dermatol. 130 (4) :1095-1106 (2010)

• Background Reference 03:

  Choi, J.A., et al. Carcinogenesis 31 (4) :543-551 (2010)

• Background Reference 04:

  Cho, K.J., et al. Am. J. Respir. Cell Mol. Biol. 42 (3) :294-303 (2010)

• Other Product Names:

  Leukotriene B4 receptor 2, LTB4-R 2, LTB4-R2, LTB4 receptor JULF2, Leukotriene B4 receptor BLT2, Seven transmembrane receptor BLTR2, LTB4R2, BLT2R, BLTR2

• Tested Applications:

  WB

• Protein ID:

  23821812

• Physical Properties:

  Liquid