Products for Research Use Only
RegisterLogin

GJA7 Antibody

CAT: 0223-58-182Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-58-182Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell closely packed transmembrane channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. Connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 is designated alpha-1 gap junction protein, whereas CX32 and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43. Connexins have four transmembrane, three intracellular, and two extracellular regions. Different tissues express different connexins, though tissue specificities overlap, and a given tissue or cell can express several different connexins. Developmental regulation of at least some of the connexin genes has been found. Embryo implantation is regulated in part by temporally changing patterns of expression of connexins in the embryo and the maternal decidua.
NCBI Gene ID
10052
Swiss Prot
P36383
Accession Number
P36383
Host
Rabbit
Reactivity
Human
Immunogen
This GJA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-120 amino acids from the N-terminal region of human GJA7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Hamster, Mouse, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
45 kDa
Fragment
Rabbit Ig
Symbol
GJC1
NCBI Official Name
Gap junction gamma-1 protein
NCBI Organism
Homo sapiens
Background Reference 01
Xiang, Q., et al., Ai Zheng 21 (6) :593-596 (2002) .
Background Reference 02
Kanter, H.L., et al., J. Mol. Cell. Cardiol. 26 (7) :861-868 (1994) .
Background Reference 03
Kaba, R.A., et al., Cell Commun. Adhes. (4-6), 339-343 (2001) .
Other Product Names
Gap junction gamma-1 protein, Connexin-45, Cx45, Gap junction alpha-7 protein, GJC1, GJA7
Tested Applications
WB, IHC-P
Protein ID
226693517
Physical Properties
Liquid

Related Products

CatalogName
29-808Gja4 Antibody
42-492GJA8 Antibody
25-372GJA3 Antibody
25-373GJA9 Antibody
28-528GJA5 Antibody
58-175GJA3 Antibody
48-409GJA1 Antibody
46-995GJA1 Antibody
22-799GJA5 Antibody
28-525GJA1 Antibody

Alternative Products

CatalogName
MBS9209550-01GJA7 Antibody (N-term)
ASA-B0486Connexin 45/GJA7 Antibody
GTR18974661GJA7 Antibody Blocking peptide
DF4080-01Connexin 45 / GJA7 Antibody
APR04056G-01GJA7 Antibody (N-term) [APR04056G]
MBS177739-01Anti-Connexin 45/GJA7 Antibody
OAAB11377-400ULGJA7 Antibody - N-terminal region
MBS1750928-01Anti-Connexin 45/GJA7 Picoband Antibody
MBS9221333-01GJA7 Antibody (N-term) Blocking Peptide
ER1803-93Connexin 45 / GJA7 / Cx45 Rabbit Polyclonal Antibody

Popular Products