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GJA1 Antibody

CAT: 0223-28-525Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-28-525Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Gap junction protein, alpha 1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. Connexin 43 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. Connexin 43 is targeted by several protein kinases that regulate myocardial cell-cell coupling. A related intron-less connexin 43 pseudogene, GJA1P, has been mapped to chromosome 5.
NCBI Gene ID
2697
Swiss Prot
Q53FJ6
Accession Number
NP_000156
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GJA1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer, Signal Transduction, Immunology
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1309 - Human Placenta Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GJA1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
42 kDa
Applications Notes
GJA1 antibody can be used for detection of GJA1 by ELISA at 1:312500. GJA1 antibody can be used for detection of GJA1 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
GJA1
NCBI Official Name
Gap junction protein, alpha 1, 43kDa
NCBI Organism
Homo sapiens
Background Reference 01
Gellhaus, A., et al., (2004) J. Biol. Chem. 279 (35), 36931-36942.
Other Product Names
GJA1, HSS, CMDR, CX43, GJAL, ODDD, AVSD3, HLHS1, DFNB38
Tested Applications
ELISA, WB
Protein ID
4504001
Physical Properties
Liquid

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CSB-PA009443GA01HUGJA1 Antibody

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