ATF5 Antibody

CAT: 0223-58-150Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-150Size:400 µL
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Background
Transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4.
NCBI Gene ID
22809
Swiss Prot
Q9Y2D1
Accession Number
Q9Y2D1
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This ATF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-216 amino acids from the C-terminal region of human ATF5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
31 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ATF5
NCBI Official Name
Cyclic AMP-dependent transcription factor ATF-5
NCBI Organism
Homo sapiens
Background Reference 01
Wei, Y., et al. J. Biochem. 148 (2) :171-178 (2010)
Background Reference 02
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 03
Tomppo, L., et al. Biol. Psychiatry 65 (12) :1055-1062 (2009)
Background Reference 04
Li, G., et al. Mol. Cancer Res. 7 (6) :933-943 (2009)
Other Product Names
Cyclic AMP-dependent transcription factor ATF-5, cAMP-dependent transcription factor ATF-5, Activating transcription factor 5, Transcription factor ATFx, ATF5, ATFX
Tested Applications
WB
Protein ID
308153647
Physical Properties
Liquid

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