ATF5 Antibody

• Background:

  Transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4.

• NCBI Gene ID:

  22809

• Swiss Prot:

  Q9Y2D1

• Accession Number:

  Q9Y2D1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This ATF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-216 amino acids from the C-terminal region of human ATF5.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  31 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  ATF5

• NCBI Official Name:

  Cyclic AMP-dependent transcription factor ATF-5

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Wei, Y., et al. J. Biochem. 148 (2) :171-178 (2010)

• Background Reference 02:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 03:

  Tomppo, L., et al. Biol. Psychiatry 65 (12) :1055-1062 (2009)

• Background Reference 04:

  Li, G., et al. Mol. Cancer Res. 7 (6) :933-943 (2009)

• Other Product Names:

  Cyclic AMP-dependent transcription factor ATF-5, cAMP-dependent transcription factor ATF-5, Activating transcription factor 5, Transcription factor ATFx, ATF5, ATFX

• Tested Applications:

  WB

• Protein ID:

  308153647

• Physical Properties:

  Liquid