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KLK12 Antibody

CAT: 0223-58-114Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-114Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq].
NCBI Gene ID
43849
Swiss Prot
Q9UKR0
Accession Number
Q9UKR0
Host
Rabbit
Reactivity
Human
Immunogen
This KLK12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-113 amino acids from the Central region of human KLK12.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
27 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
KLK12
NCBI Official Name
Kallikrein-12
NCBI Organism
Homo sapiens
Background Reference 01
Klein, R.J., et al. Cancer Prev Res (Phila) 3 (5) :611-619 (2010)
Background Reference 02
Memari, N., et al. Biol. Chem. 388 (4) :427-435 (2007)
Background Reference 03
Lundwall, A., et al. Biol. Chem. 387 (6) :637-641 (2006)
Background Reference 04
Shinmura, K., et al. Hum. Mutat. 24 (3) :273-274 (2004)
Other Product Names
Kallikrein-12, 3421-, Kallikrein-like protein 5, KLK-L5, KLK12, KLKL5
Tested Applications
WB
Protein ID
9296989
Physical Properties
Liquid

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