KLK14 Antibody

• Background:

  Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. An additional transcript variant has been described but its full length nature has not been determined.

• NCBI Gene ID:

  43847

• Swiss Prot:

  Q9P0G3

• Accession Number:

  Q9P0G3

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This KLK14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human KLK14.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  29 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  KLK14

• NCBI Official Name:

  Kallikrein-14

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Klein, R.J., et al. Cancer Prev Res (Phila Pa) 3 (5) :611-619 (2010)

• Background Reference 02:

  Hashem, N.N., et al. Int. J. Biol. Markers 25 (1) :32-37 (2010)

• Background Reference 03:

  Emami, N., et al. Biol. Chem. 390 (9) :921-929 (2009)

• Background Reference 04:

  Lai, J., et al. Mol. Cancer Res. 7 (1) :129-141 (2009)

• Other Product Names:

  Kallikrein-14, hK14, 3421-, Kallikrein-like protein 6, KLK-L6, KLK14, KLKL6

• Tested Applications:

  WB

• Protein ID:

  251757292

• Physical Properties:

  Liquid