KLK10 Antibody

• Background:

  Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq].

• NCBI Gene ID:

  5655

• Swiss Prot:

  O43240

• Accession Number:

  O43240

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This KLK10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-51 amino acids from the N-terminal region of human KLK10.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  30 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  KLK10

• NCBI Official Name:

  Kallikrein-10

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Batra, J., et al. Int. J. Gynecol. Cancer 20 (4) :529-536 (2010)

• Background Reference 02:

  Klein, R.J., et al. Cancer Prev Res (Phila) 3 (5) :611-619 (2010)

• Background Reference 03:

  Papageorgis, P., et al. Cancer Res. 70 (3) :968-978 (2010)

• Background Reference 04:

  Lu, C.Y., et al. Genes Chromosomes Cancer 48 (12) :1057-1068 (2009)

• Other Product Names:

  Kallikrein-10, 3421-, Normal epithelial cell-specific 1, Protease serine-like 1, KLK10, NES1, PRSSL1

• Tested Applications:

  WB

• Physical Properties:

  Liquid