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KLK10 Antibody

CAT: 0223-57-815Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-815Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq].
NCBI Gene ID
5655
Swiss Prot
O43240
Accession Number
O43240
Host
Rabbit
Reactivity
Human
Immunogen
This KLK10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-51 amino acids from the N-terminal region of human KLK10.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
30 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
KLK10
NCBI Official Name
Kallikrein-10
NCBI Organism
Homo sapiens
Background Reference 01
Batra, J., et al. Int. J. Gynecol. Cancer 20 (4) :529-536 (2010)
Background Reference 02
Klein, R.J., et al. Cancer Prev Res (Phila) 3 (5) :611-619 (2010)
Background Reference 03
Papageorgis, P., et al. Cancer Res. 70 (3) :968-978 (2010)
Background Reference 04
Lu, C.Y., et al. Genes Chromosomes Cancer 48 (12) :1057-1068 (2009)
Other Product Names
Kallikrein-10, 3421-, Normal epithelial cell-specific 1, Protease serine-like 1, KLK10, NES1, PRSSL1
Tested Applications
WB
Physical Properties
Liquid

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