PCGF2 Antibody

CAT: 0223-58-091Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-091Size:400 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.
NCBI Gene ID
7703
Swiss Prot
P35227
Accession Number
P35227
Host
Rabbit
Reactivity
Human
Immunogen
This PCGF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-150 amino acids from the Central region of human PCGF2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
38 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PCGF2
NCBI Official Name
Polycomb group RING finger protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Jung, J.H., et al. Biochem. Biophys. Res. Commun. 400 (4) :523-530 (2010)
Background Reference 02
Zhang, X.W., et al. Mol. Cancer 9, 40 (2010) :
Background Reference 03
Wang, W., et al. Int. J. Cancer 125 (12) :2836-2843 (2009)
Background Reference 04
Zhang, J., et al. Biochem. Biophys. Res. Commun. 375 (2) :252-255 (2008)
Other Product Names
Polycomb group RING finger protein 2, DNA-binding protein Mel-18, RING finger protein 110, Zinc finger protein 144, PCGF2, MEL18, RNF110, ZNF144
Tested Applications
WB
Protein ID
462585
Physical Properties
Liquid

Related Products

CatalogName
28-084PCGF3 Antibody
28-083PCGF3 Antibody
22-956PCGF3 Antibody
22-140PCGF1 Antibody
19-841PCGF6 Antibody
60-168PCGF6 Antibody
28-036PCGF4 Antibody
64-160WAS Antibody
13-349WAS Antibody
60-596WAS Antibody

Alternative Products

CatalogName
C45455-01PCGF2 Antibody
MBS9206143-01PCGF2 Antibody (Center)
MBS9433151-01PCGF2 Polyclonal Antibody
STJ119456Anti-PCGF2 antibody
abx317082-01PCGF2 Antibody (Biotin)
abx317080-01PCGF2 Antibody (HRP)
BS78237PCGF2 polyclonal antibody
abx317081-01PCGF2 Antibody (FITC)
CSB-CL017606HUPCGF2

Popular Products