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DVL2 Antibody

CAT: 0223-58-081Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-081Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.
NCBI Gene ID
1856
Swiss Prot
O14641
Accession Number
O14641
Host
Rabbit
Reactivity
Human
Immunogen
This DVL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 588-617 amino acids from the C-terminal region of human DVL2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
79 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
DVL2
NCBI Official Name
Segment polarity protein dishevelled homolog DVL-2
NCBI Organism
Homo sapiens
Background Reference 01
Inkster, B., et al. Neuroimage 53 (3) :908-917 (2010)
Background Reference 02
Kikuchi, K., et al. EMBO J. 29 (20) :3470-3483 (2010)
Background Reference 03
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 04
Gao, C., et al. Nat. Cell Biol. 12 (8) :781-790 (2010)
Other Product Names
Segment polarity protein dishevelled homolog DVL-2, Dishevelled-2, DSH homolog 2, DVL2
Tested Applications
WB
Physical Properties
Liquid

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