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TCEB1 Antibody

CAT: 223-58-012Size: 400 µLDry Ice: NoHazardous: No
400 µLSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
NCBI Gene ID
6921
Swiss Prot
Q15369
Accession Number
Q15369
Host
Rabbit
Reactivity
Human
Immunogen
This TCEB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the C-terminal region of human TCEB1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
12 kDa
Fragment
Rabbit Ig
Symbol
TCEB1
NCBI Official Name
Transcription elongation factor B polypeptide 1
NCBI Organism
Homo sapiens
Background Reference 01
Marcsisin, S.R., et al. J. Mol. Biol. 402 (5) :892-904 (2010)
Background Reference 02
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 03
Lievens, S., et al. J. Proteome Res. 8 (2) :877-886 (2009)
Background Reference 04
Jalava, S.E., et al. Int. J. Cancer 124 (1) :95-102 (2009)
Other Product Names
Transcription elongation factor B polypeptide 1, Elongin 15 kDa subunit, Elongin-C, EloC, RNA polymerase II transcription factor SIII subunit C, SIII p15, TCEB1
Tested Applications
WB, IHC-P
Protein ID
32699511
Physical Properties
Liquid

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