TGIF2 Antibody

• Background:

  The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor. The encoded protein appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and overexpressed in some ovarian cancers, and mutations in this gene can cause holoprosencephaly.

• NCBI Gene ID:

  10052794360436

• Swiss Prot:

  Q9GZN2

• Accession Number:

  Q9GZN2

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This TGIF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the C-terminal region of human TGIF2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  26 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  TGIF2

• NCBI Official Name:

  Homeobox protein TGIF2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Watanabe, T., et al. Jpn. J. Cancer Res. 93 (10) :1114-1122 (2002)

• Background Reference 02:

  Deloukas, P., et al. Nature 414 (6866) :865-871 (2001)

• Background Reference 03:

  Melhuish, T.A., et al. J. Biol. Chem. 276 (34) :32109-32114 (2001)

• Background Reference 04:

  Imoto, I., et al. Biochem. Biophys. Res. Commun. 276 (1) :264-270 (2000)

• Other Product Names:

  Homeobox protein TGIF2, 5'-TG-3'-interacting factor 2, TGF-beta-induced transcription factor 2, TGFB-induced factor 2, TGIF2

• Tested Applications:

  WB, Flow

• Protein ID:

  27805750

• Physical Properties:

  Liquid