Products for Research Use Only

TGIF2 Antibody

CAT: 0223-58-005Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-005Size:400 µL
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Background
The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor. The encoded protein appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and overexpressed in some ovarian cancers, and mutations in this gene can cause holoprosencephaly.
NCBI Gene ID
10052794360436
Swiss Prot
Q9GZN2
Accession Number
Q9GZN2
Host
Rabbit
Reactivity
Human
Immunogen
This TGIF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the C-terminal region of human TGIF2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
26 kDa
Fragment
Rabbit Ig
Symbol
TGIF2
NCBI Official Name
Homeobox protein TGIF2
NCBI Organism
Homo sapiens
Background Reference 01
Watanabe, T., et al. Jpn. J. Cancer Res. 93 (10) :1114-1122 (2002)
Background Reference 02
Deloukas, P., et al. Nature 414 (6866) :865-871 (2001)
Background Reference 03
Melhuish, T.A., et al. J. Biol. Chem. 276 (34) :32109-32114 (2001)
Background Reference 04
Imoto, I., et al. Biochem. Biophys. Res. Commun. 276 (1) :264-270 (2000)
Other Product Names
Homeobox protein TGIF2, 5'-TG-3'-interacting factor 2, TGF-beta-induced transcription factor 2, TGFB-induced factor 2, TGIF2
Tested Applications
WB, Flow
Protein ID
27805750
Physical Properties
Liquid