ECT2 Antibody

• Background:

  The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.

• NCBI Gene ID:

  1894

• Swiss Prot:

  Q9H8V3

• Accession Number:

  Q9H8V3

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ECT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 597-625 amino acids from the Central region of human ECT2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  104 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  ECT2

• NCBI Official Name:

  Protein ECT2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Justilien, V., et al. Oncogene 28 (41) :3597-3607 (2009)

• Background Reference 02:

  Burkard, M.E., et al. PLoS Biol. (5), E1000111 (2009) :

• Background Reference 03:

  Wolfe, B.A., et al. PLoS Biol. (5), E1000110 (2009) :

• Background Reference 04:

  Hirata, D., et al. Clin. Cancer Res. 15 (1) :256-266 (2009)

• Other Product Names:

  Protein ECT2, Epithelial cell-transforming sequence 2 oncogene, ECT2

• Tested Applications:

  WB, IHC-P

• Protein ID:

  357529579

• Physical Properties:

  Liquid