SDC3 Antibody

• Background:

  The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity.

• NCBI Gene ID:

  9672

• Swiss Prot:

  O75056

• Accession Number:

  O75056

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SDC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 413-442 amino acids from the C-terminal region of human SDC3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  45 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SDC3

• NCBI Official Name:

  Syndecan-3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Schuring, A.N., et al. J. Mol. Med. 87 (12) :1241-1250 (2009)

• Background Reference 02:

  Marzioni, D., et al. IntImmunopathol Pharmacol 22 (3) :627-638 (2009)

• Background Reference 03:

  Yao, J., et al. Dig. Dis. Sci. 54 (4) :895-901 (2009)

• Background Reference 04:

  Landgraf, P., et al. J. Biol. Chem. 283 (36) :25036-25045 (2008)

• Other Product Names:

  Syndecan-3, SYND3, SDC3, KIAA0468

• Tested Applications:

  WB

• Physical Properties:

  Liquid