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UBE4A Antibody

CAT: 0223-57-907Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-907Size:400 µL
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Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly.
NCBI Gene ID
9354
Swiss Prot
Q14139
Accession Number
Q14139
Host
Rabbit
Reactivity
Human
Immunogen
This UBE4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 451-479 amino acids from the Central region of human UBE4A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
123 kDa
Fragment
Rabbit Ig
Symbol
UBE4A
NCBI Official Name
Ubiquitin conjugation factor E4 A
NCBI Organism
Homo sapiens
Background Reference 01
Shi, D., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (38) :16275-16280 (2009)
Background Reference 02
Sakiyama, T., et al. Inflamm. Bowel Dis. 14 (3) :310-317 (2008)
Background Reference 03
Yang, Y., et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 23 (6) :504-506 (2007)
Background Reference 04
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Other Product Names
HGNC:12499
Tested Applications
WB, IHC-P
Physical Properties
Liquid