Products for Research Use Only
RegisterLogin

SNAP23 Antibody

CAT: 0223-57-840Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-57-840Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
NCBI Gene ID
8773
Swiss Prot
O00161
Accession Number
O00161
Host
Rabbit
Reactivity
Human
Immunogen
This SNAP23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-199 amino acids from the C-terminal region of human SNAP23.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
23 kDa
Fragment
Rabbit Ig
Symbol
SNAP23
NCBI Official Name
Synaptosomal-associated protein 23
NCBI Organism
Homo sapiens
Background Reference 01
Greaves, J., et al. J. Biol. Chem. 285 (32) :24629-24638 (2010)
Background Reference 02
Bostrom, P., et al. Diabetes 59 (8) :1870-1878 (2010)
Background Reference 03
Ban, H.J., et al. BMC Genet. 11, 26 (2010) :
Background Reference 04
Kean, M.J., et al. J. Cell. Sci. 122 (PT 22), 4089-4098 (2009) :
Other Product Names
Synaptosomal-associated protein 23, SNAP-23, Vesicle-membrane fusion protein SNAP-23, SNAP23
Tested Applications
WB, IHC-P
Physical Properties
Liquid

Related Products

CatalogName
42-631PSNAP23 Peptide
42-821PSNAP23 Peptide
28-020SNAPC3 Antibody
50-190SNAP25 Antibody
45-149SNAP25 Antibody
31-133SNAP25 Antibody
59-662SNAP25 Antibody
19-330SNAP29 Antibody
60-380SNAPC3 Antibody
13-354SNAP25 Antibody

Alternative Products

CatalogName
70R-20417SNAP23 antibody

Popular Products