SNAPC3 Antibody

• Background:

  Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.

• NCBI Gene ID:

  6619

• Swiss Prot:

  Q92966

• Accession Number:

  Q92966

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SNAPC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-171 amino acids from the Central region of human SNAPC3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Monkey

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  47 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SNAPC3

• NCBI Official Name:

  SnRNA-activating protein complex subunit 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Wu, C., et al. Proteomics 7 (11) :1775-1785 (2007)

• Background Reference 02:

  Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)

• Background Reference 03:

  Jawdekar, G.W., et al. J. Biol. Chem. 281 (41) :31050-31060 (2006)

• Background Reference 04:

  Humphray, S.J., et al. Nature 429 (6990) :369-374 (2004)

• Other Product Names:

  SnRNA-activating protein complex subunit 3, SNAPc subunit 3, Proximal sequence element-binding transcription factor subunit beta, PSE-binding factor subunit beta, PTF subunit beta, Small nuclear RNA-activating complex polypeptide 3, snRNA-activating protein complex 50 kDa subunit, SNAPc 50 kDa subunit, SNAPC3, SNAP50

• Tested Applications:

  WB

• Protein ID:

  8134719

• Physical Properties:

  Liquid