PPP6C Antibody

• Background:

  This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. Splice variants encoding different protein isoforms exist. The pseudogene of this gene is located on chromosome X.

• NCBI Gene ID:

  5537

• Swiss Prot:

  O00743

• Accession Number:

  O00743

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PPP6C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 264-293 amino acids from the C-terminal region of human PPP6C.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  35 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PPP6C

• NCBI Official Name:

  Serine/threonine-protein phosphatase 6 catalytic subunit

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Douglas, P., et al. Mol. Cell. Biol. 30 (6) :1368-1381 (2010)

• Background Reference 02:

  Dema, B., et al. Genes Immun. 10 (7) :659-661 (2009)

• Background Reference 03:

  Morales-Johansson, H., et al. PLoS ONE (7), E6331 (2009) :

• Background Reference 04:

  Mi, J., et al. PLoS ONE (2), E4395 (2009) :

• Other Product Names:

  Serine/threonine-protein phosphatase 6 catalytic subunit, PP6C, Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed, PPP6C, PPP6

• Tested Applications:

  WB

• Physical Properties:

  Liquid