FDFT1 Antibody

• Background :

  This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.

• NCBI Gene ID :

  2222

• Swiss Prot :

  P37268

• Accession Number :

  P37268

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This FDFT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-361 amino acids from the C-terminal region of human FDFT1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Obesity, Neuroscience

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  48 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  FDFT1

• NCBI Official Name :

  Squalene synthase

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Chalasani, N., et al. Gastroenterology 139 (5) :1567-1576 (2010)

• Background Reference 02 :

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 03 :

  Kovanen, L., et al. Alcohol Alcohol. 45 (4) :303-311 (2010)

• Background Reference 04 :

  Lipkin, S.M., et al. Cancer Prev Res (Phila) 3 (5) :597-603 (2010)

• Other Product Names :

  Squalene synthase, SQS, SS, FPP:FPP farnesyltransferase, Farnesyl-diphosphate farnesyltransferase, FDFT1

• Tested Applications :

  WB

• Protein ID :

  585126

• Physical Properties :

  Liquid