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FDFT1 Antibody

CAT: 0223-57-820Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-820Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.
NCBI Gene ID
2222
Swiss Prot
P37268
Accession Number
P37268
Host
Rabbit
Reactivity
Human
Immunogen
This FDFT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-361 amino acids from the C-terminal region of human FDFT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
48 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
FDFT1
NCBI Official Name
Squalene synthase
NCBI Organism
Homo sapiens
Background Reference 01
Chalasani, N., et al. Gastroenterology 139 (5) :1567-1576 (2010)
Background Reference 02
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 03
Kovanen, L., et al. Alcohol Alcohol. 45 (4) :303-311 (2010)
Background Reference 04
Lipkin, S.M., et al. Cancer Prev Res (Phila) 3 (5) :597-603 (2010)
Other Product Names
Squalene synthase, SQS, SS, FPP:FPP farnesyltransferase, Farnesyl-diphosphate farnesyltransferase, FDFT1
Tested Applications
WB
Protein ID
585126
Physical Properties
Liquid

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