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IDE Antibody

CAT: 0223-57-818Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-818Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IDE belongs to a protease family responsible for intercellular peptide signalling. Though its role in the cellular processing of insulin has not yet been defined, insulin-degrading enzyme is thought to be involved in the termination of the insulin response.
NCBI Gene ID
3416
Swiss Prot
P14735
Accession Number
P14735
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This IDE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 406-435 amino acids from the Central region of human IDE.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat, Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
118 kDa
Fragment
Rabbit Ig
Symbol
IDE
NCBI Official Name
Insulin-degrading enzyme
NCBI Organism
Homo sapiens
Background Reference 01
Vepsalainen, S., J. Med. Genet. 44 (9), 606-608 (2007)
Background Reference 02
Kim, M., J. Biol. Chem. 282 (11), 7825-7832 (2007)
Background Reference 03
Radulescu, R.T., Int. J. Oncol. 30 (1), 73-80 (2007)
Background Reference 04
Li, Q., Cell 127 (2), 305-316 (2006)
Other Product Names
Insulin-degrading enzyme, Abeta-degrading protease, Insulin protease, Insulinase, Insulysin, IDE
Tested Applications
WB, IHC-P
Protein ID
215274252
Physical Properties
Liquid

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