PRPF31 Antibody

• Background:

  This gene encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes. When the gene product is added to the spliceosome complex, activation occurs.

• NCBI Gene ID:

  26121

• Swiss Prot:

  Q8WWY3

• Accession Number:

  Q8WWY3

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PRPF31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 334-361 amino acids from the C-terminal region of human PRPF31.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Zebrafish, Mouse, Xenopus

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  55 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PRPF31

• NCBI Official Name:

  U4/U6 small nuclear ribonucleoprotein Prp31

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Schneider, M., et al. Nat. Struct. Mol. Biol. 17 (2) :216-221 (2010)

• Background Reference 02:

  Bujakowska, K., et al. Invest. Ophthalmol. Vis. Sci. 50 (12) :5927-5933 (2009)

• Background Reference 03:

  Potkin, S.G., et al. PLoS ONE (8), E6501 (2009) :

• Background Reference 04:

  Liu, S., et al. Science 316 (5821) :115-120 (2007)

• Other Product Names:

  U4/U6 small nuclear ribonucleoprotein Prp31, Pre-mRNA-processing factor 31, Serologically defined breast cancer antigen NY-BR-99, U4/U6 snRNP 61 kDa protein, Protein 61K, hPrp31, PRPF31, PRP31

• Tested Applications:

  WB

• Protein ID:

  90101442

• Physical Properties:

  Liquid