PRPF3 Antibody

• Background:

  The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. PRPF3 is 1 of several proteins that associate with U4 and U6 snRNPs.The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. PRPF3 is 1 of several proteins that associate with U4 and U6 snRNPs.

• NCBI Gene ID:

  9129

• Swiss Prot:

  O43395

• Accession Number:

  NP_004689

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PRPF3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PRPF3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  75 kDa

• Applications Notes:

  PRPF3 antibody can be used for detection of PRPF3 by ELISA at 1:62500. PRPF3 antibody can be used for detection of PRPF3 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  PRPF3

• NCBI Official Name:

  Pre-mRNA processing factor 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rual, J.F., (2005) Nature 437 (7062), 1173-1178.

• Other Product Names:

  PRPF3, PRP3, RP18, HPRP3, Prp3p, HPRP3P, SNRNP90

• Tested Applications:

  ELISA, WB

• Protein ID:

  4758556

• Physical Properties:

  Liquid