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GABRB2 Antibody

CAT: 0223-57-799Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-799Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion.
NCBI Gene ID
2561
Swiss Prot
P47870
Accession Number
P47870
Host
Rabbit
Reactivity
Human
Immunogen
This GABRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-374 amino acids from the C-terminal region of human GAB_2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
59 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:500
Symbol
GABRB2
NCBI Official Name
Gamma-aminobutyric acid receptor subunit beta-2
NCBI Organism
Homo sapiens
Background Reference 01
Lo, W.Y., et al. J. Biol. Chem. 285 (41) :31348-31361 (2010)
Background Reference 02
Green, E.K., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (7), 1347-1349 (2010) :
Background Reference 03
Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Background Reference 04
Chen, J., et al. Biochem. Soc. Trans. 37 (PT 6), 1415-1418 (2009) :
Other Product Names
Gamma-aminobutyric acid receptor subunit beta-2, GABA (A) receptor subunit beta-2, GABRB2
Tested Applications
WB
Protein ID
292495010
Physical Properties
Liquid

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