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GABRG2 Antibody

CAT: 0223-55-075Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-075Size:400 µL
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Background
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.
NCBI Gene ID
2566
Swiss Prot
P18507
Accession Number
P18507
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This GABRG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-224 amino acids from the Central region of human GABRG2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat, Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
54 kDa
Fragment
Rabbit Ig
Symbol
GABRG2
NCBI Official Name
Gamma-aminobutyric acid receptor subunit gamma-2
NCBI Organism
Homo sapiens
Background Reference 01
Green, E.K., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (7), 1347-1349 (2010) :
Background Reference 02
Jansen, L.A., et al. Epilepsia 51 (8) :1456-1467 (2010)
Background Reference 03
Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Background Reference 04
Shi, X., et al. J. Hum. Genet. 55 (6) :375-378 (2010)
Other Product Names
Gamma-aminobutyric acid receptor subunit gamma-2, GABA (A) receptor subunit gamma-2, GABRG2
Tested Applications
WB, IHC-P
Protein ID
116242488
Physical Properties
Liquid

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