Products for Research Use Only

PTGIR Antibody

CAT: 0223-57-726Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-726Size:400 µL
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Background
The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor.
NCBI Gene ID
5739
Swiss Prot
P43119
Accession Number
P43119
Host
Rabbit
Reactivity
Human
Immunogen
This PTGIR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-238 amino acids from the Central region of human PTGIR.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Symbol
PTGIR
NCBI Official Name
Prostacyclin receptor
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Ibrahim, S., et al. Arterioscler. Thromb. Vasc. Biol. 30 (9) :1802-1809 (2010)
Background Reference 03
Reid, H.M., et al. J. Biol. Chem. 285 (24) :18709-18726 (2010)
Background Reference 04
Muto, A., et al. Int Angiol 29 (2 SUPPL), 43-48 (2010) :
Other Product Names
Prostacyclin receptor, Prostaglandin I2 receptor, PGI receptor, PGI2 receptor, Prostanoid IP receptor, PTGIR, PRIPR
Tested Applications
WB, IHC-P
Protein ID
1172500
Physical Properties
Liquid