Products for Research Use Only
RegisterLogin

PTPRE Antibody

CAT: 0223-57-711Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-57-711Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels. [provided by RefSeq].
NCBI Gene ID
5791
Swiss Prot
P23469
Accession Number
P23469
Host
Rabbit
Reactivity
Human
Immunogen
This PTPRE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-163 amino acids from the N-terminal region of human PTPRE.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
81 kDa
Fragment
Rabbit Ig
Symbol
PTPRE
NCBI Official Name
Receptor-type tyrosine-protein phosphatase epsilon
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34 (5) :800-812 (2010)
Background Reference 03
Barr, A.J., et al. Cell 136 (2) :352-363 (2009)
Background Reference 04
Kraut-Cohen, J., et al. J. Biol. Chem. 283 (8) :4612-4621 (2008)
Other Product Names
Receptor-type tyrosine-protein phosphatase epsilon, Protein-tyrosine phosphatase epsilon, R-PTP-epsilon, PTPRE
Tested Applications
WB, IHC-P
Protein ID
126471
Physical Properties
Liquid

Related Products

CatalogName
18-424PTPRA Antibody
15-451PTPRG Antibody
57-787PTPRN Antibody
46-702PTPRH Antibody
XW-7816PTPRF Antibody
22-191PTPRN Antibody
19-666PTPRF Antibody
42-804PTPRB Antibody
46-252PTPRM Antibody
30-064PTPRR Antibody

Alternative Products

CatalogName
10R-5526PTPRE antibody

Popular Products