PTPRN Antibody

CAT: 0223-22-191Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-22-191Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.
NCBI Gene ID
5798
Swiss Prot
Q16849
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 600-889 of human PTPRN (NP_001186693.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 66kDa
Fragment
IgG
Symbol
PTPRN
Positive Control 2
NIH/3T3
Positive Control 3
Raji
Positive Control 4
Mouse brain
Positive Control 5
Rat brain
NCBI Official Name
Protein tyrosine phosphatase, receptor type, N
NCBI Organism
Homo sapiens
Other Product Names
PTPRN, FLJ16131, IA-2, IA-2/PTP, IA2, ICA512, R-PTP-N
Tested Applications
WB, IHC
Physical Properties
Liquid

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