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IL9R Antibody

CAT: 0223-57-677Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-677Size:400 µL
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Background
The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9) . The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene.
NCBI Gene ID
3581
Swiss Prot
Q01113
Accession Number
Q01113
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This IL9R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-199 amino acids from the Central region of human IL9R.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
57 kDa
Fragment
Rabbit Ig
Symbol
IL9R
NCBI Official Name
Interleukin-9 receptor
NCBI Organism
Homo sapiens
Background Reference 01
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Background Reference 02
McCanlies, E.C., et al. J. Occup. Environ. Med. 52 (7) :680-684 (2010)
Background Reference 03
Schuurhof, A., et al. Pediatr. Pulmonol. 45 (6) :608-613 (2010)
Background Reference 04
Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :
Other Product Names
Interleukin-9 receptor, IL-9 receptor, IL-9R, CD129, IL9R
Tested Applications
WB, IHC-P
Protein ID
116242526
Physical Properties
Liquid

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