Mouse Mapk8 Antibody

CAT: 0223-57-885Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-885Size:400 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mapk8 responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. Phosphorylates heat shock factor protein 4 (HSF4) (By similarity) .
NCBI Gene ID
26419
Swiss Prot
Q91Y86
Accession Number
Q91Y86
Host
Rabbit
Reactivity
Human
Immunogen
This Mouse Mapk8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the Central region of mouse Mapk8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat, Xenopus
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
44 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Mapk8
NCBI Official Name
Mitogen-activated protein kinase 8
NCBI Organism
Mus musculus
Background Reference 01
Sherrin, T., et al. J. Neurosci. 30 (40) :13348-13361 (2010)
Background Reference 02
Morel, C., et al. Mol. Cell. Biol. 30 (19) :4616-4625 (2010)
Background Reference 03
Gao, D., et al. J. Biol. Chem. 285 (39) :29965-29973 (2010)
Background Reference 04
Han, J.S., et al. Anticancer Res. 30 (9) :3407-3412 (2010)
Other Product Names
Mitogen-activated protein kinase 8, MAP kinase 8, MAPK 8, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1, Mapk8, Jnk1, Prkm8
Tested Applications
WB
Physical Properties
Liquid

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