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MAPK3 Antibody

CAT: 0223-62-761Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-62-761Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MAPK3 is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets.
NCBI Gene ID
5595
Swiss Prot
P27361
Accession Number
P27361
Host
Rabbit
Reactivity
Human
Immunogen
This MAPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182-211 amino acids from human MAPK3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Drosophila, Bovine, Mouse, Rat, Xenopus, C. Elegans
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
43 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MAPK3
NCBI Official Name
Mitogen-activated protein kinase 3
NCBI Organism
Homo sapiens
Background Reference 01
Munshi, H.G., et al., J. Biol. Chem. 279 (37) :39042-39050 (2004) .
Background Reference 02
Mukherjee, S., et al., Infect. Immun. 72 (9) :5274-5282 (2004) .
Background Reference 03
Sebkova, L., et al., Infect. Immun. 72 (9) :5019-5026 (2004) .
Background Reference 04
Huang, H.M., et al., Biochem. Biophys. Res. Commun. 320 (4) :1247-1252 (2004) .
Other Product Names
Mitogen-activated protein kinase 3, MAP kinase 3, MAPK 3, ERT2, Extracellular signal-regulated kinase 1, ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase isoform p44, p44-MAPK, Microtubule-associated protein 2 kinase, p44-ERK1, MAPK3, ERK1, PRKM3
Tested Applications
WB
Protein ID
232066
Physical Properties
Liquid

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