MAPK3 Antibody

• Background:

  MAPK3 is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets.

• NCBI Gene ID:

  5595

• Swiss Prot:

  P27361

• Accession Number:

  P27361

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MAPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182-211 amino acids from human MAPK3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Drosophila, Bovine, Mouse, Rat, Xenopus, C. Elegans

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  43 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  MAPK3

• NCBI Official Name:

  Mitogen-activated protein kinase 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Munshi, H.G., et al., J. Biol. Chem. 279 (37) :39042-39050 (2004) .

• Background Reference 02:

  Mukherjee, S., et al., Infect. Immun. 72 (9) :5274-5282 (2004) .

• Background Reference 03:

  Sebkova, L., et al., Infect. Immun. 72 (9) :5019-5026 (2004) .

• Background Reference 04:

  Huang, H.M., et al., Biochem. Biophys. Res. Commun. 320 (4) :1247-1252 (2004) .

• Other Product Names:

  Mitogen-activated protein kinase 3, MAP kinase 3, MAPK 3, ERT2, Extracellular signal-regulated kinase 1, ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase isoform p44, p44-MAPK, Microtubule-associated protein 2 kinase, p44-ERK1, MAPK3, ERK1, PRKM3

• Tested Applications:

  WB

• Protein ID:

  232066

• Physical Properties:

  Liquid