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CNOT2 Antibody

CAT: 0223-57-581Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-581Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene.
NCBI Gene ID
4848
Swiss Prot
Q9NZN8
Accession Number
Q9NZN8
Host
Rabbit
Reactivity
Human
Immunogen
This CNOT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-301 amino acids from the Central region of human CNOT2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
60 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CNOT2
NCBI Official Name
CCR4-NOT transcription complex subunit 2
NCBI Organism
Homo sapiens
Background Reference 01
Lau, N.C., et al. Biochem. J. 422 (3) :443-453 (2009)
Background Reference 02
Miyasaka, T., et al. Cancer Sci. 99 (4) :755-761 (2008)
Background Reference 03
Morita, M., et al. Mol. Cell. Biol. 27 (13) :4980-4990 (2007)
Background Reference 04
Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)
Other Product Names
CCR4-NOT transcription complex subunit 2, CCR4-associated factor 2, CNOT2, CDC36, NOT2
Tested Applications
WB
Protein ID
46396017
Physical Properties
Liquid

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